What are the possible side effects of Keppra XR®?

See the Safety section for the most important information you should Forzest know about Keppra XR^®.

Keppra XR^® can cause serious side effects. Call your doctor right away if you get any of these symptoms:

• mood and behavior changes such as aggression, agitation, anger, anxiety, apathy, mood swings, depression, hostility, and irritability. A few people may get psychotic symptoms such as hallucinations (seeing or hearing things that are really not there), delusions (false or strange thoughts or beliefs) and unusual behavior.
• extreme sleepiness, tiredness, and weakness
• problems with muscle coordination (problems walking and moving)

Common side effects seen in people who take Keppra XR^® and other formulations of Keppra^® include:

• sleepiness
• weakness
• dizziness
• infection

These side effects could happen at any time but happen most often within the first four weeks of treatment.

These are not all the possible side effects of Keppra XR^®. For more information, ask your neurologist or pharmacist. If you get any side effects that concern you, call your neurologist. Call your doctor for medical advice about side effects. You may also report side effects to FDA at 1-800-FDA-1088.

IMPORTANT SAFETY INFORMATION

Keppra XR^® is a prescription medicine that is used with other medicines to treat partial onset seizures in people 16 years of age and older with epilepsy.

Keppra XR^® is generally well-tolerated, but may not be for everyone. Ask your doctor if Keppra XR^® is right for you. Like other antiepileptic drugs, Keppra XR^®may cause suicidal thoughts or actions in a very small number of people, about 1 in 500 people taking it. Patients should call their healthcare provider right away if they have depression, mood problems, or suicidal thoughts or behavior while taking Keppra XR^®. Keppra XR^® may cause extreme sleepiness, tiredness, and weakness, and problems with muscle coordination. Keppra XR^® may also cause mood and behavior changes including psychotic symptoms such as hallucinations, delusions, and unusual behavior. Call your healthcare provider right away if you have any of these symptoms. The most common side effects seen with Keppra XR^® and other formulations of Keppra^® include sleepiness, weakness, dizziness, and infection. Do not stop taking Keppra XR^® unless instructed by your healthcare provider. Stopping a seizure medication all at once can cause seizures that will not stop, a very serious problem. Call your doctor for medical advice about side effects. You may also report side effects to FDA at 1-800-FDA-1088 or go to www.fda.gov/medwatch or contact UCB, Inc. at 1-866-822-0068.

Please see Keppra XR^® Medication Guide and Full Prescribing Information for additional important patient information.

*With this coupon, you pay the first $25 of your Keppra XR^® or Keppra^® co-pay and we pay your remaining out-of-pocket expense up to a maximum of $30. This coupon may not be reproduced and must accompany a valid, signed Keppra XR^®prescription. No cash value. Offer not valid for prescriptions reimbursed or paid under any government health insurance program (e.g., Medicaid, Medicare) or any private payer in Massachusetts or where otherwise prohibited by law. Patients are responsible for reporting this rebate to any private insurer that covers any part of the prescription. Offer expires on 12/31/11. UCB may cancel or alter this program at any time without notice.